liver regeneration

Introduction: About 41,260 new cases (28,600 in men and 12,660 in women) over liver cancer will be diagnosed in 2022 according to the American Cancer Society website. A model resecting approximately 60% of the liver by weight in cynomolgus monkeys is valuable in evaluating potential therapies that encourage natural regrowth of the liver post resection in human patients. Methods: Spanning three separate studies, a laparotomy was performed on a total of 26 animals, resecting approximately 60% of the total liver volume (by weight) of each animal’s liver. Liver volume was calculated based on historical organ (liver) weights measured at necropsy, determined [...]