General Session

Presenter: Jose Negron-Garcia, Cook Research Incorporated Background: In vivo models of deep vein thrombosis (DVT) have been described in rodents, non-human primates, and swine. However, these models typically require major surgery or they are not suitable for testing medical devices intended for humans. A large-animal model of DVT produced by minimally invasive methods may result in a more clinically-relevant model. Purpose: In this series of model development studies, we evaluated the ability to produce both primary and in-stent DVT in domestic swine between 2 and 28 days. Methods: Vascular access was obtained in the left external jugular and bilateral femoral veins. [...]

Presenters: Darcy Gagne, Becton Dickinson Introduction Porcine mammary anatomy is poorly understood and difficult to differentiate macroscopically. The objective of this study was to characterize the macro- and microanatomy of porcine breast tissue and draw comparisons with human breast tissue anatomy. Methods Macroscopic and microscopic anatomy of porcine mammary tissue was compared utilizing samples from an adult, non-parous female Yucatan swine prepared utilizing various methods: freezing at -80°F/ cut with a bandsaw to a thickness of 0.5 cm/ post-fixation in formalin; freezing at -20°F/ cut with a bandsaw to a thickness of 0.5 cm/ post-fixation in formalin; or formalin fixed and [...]