From this speaker
“What Do I Do Now” – Roundtable Discussion
Date: Thursday, September 15, 2022
Time: 11:00 am
Time: 11:00 am
Characterization of an Endovascularly-induced Model of Deep Vein Thrombosis in Domestic Swine
Date: Thursday, September 18, 2025
Time: 3:30 pm
Presenter: Jose Negron-Garcia, Cook Research Incorporated Background: In vivo models of deep vein thrombosis (DVT) have been described in rodents, non-human primates, and swine. However, these models typically require major surgery or they are not suitable for testing medical devices intended for humans. A large-animal model of DVT produced by minimally invasive methods may result in a more clinically-relevant model. Purpose: In this series of model development studies, we evaluated the ability to produce both primary and in-stent DVT in domestic swine between 2 and 28 days. Methods: Vascular access was obtained in the left external jugular and bilateral femoral veins. [...]
Time: 3:30 pm
Presenter: Jose Negron-Garcia, Cook Research Incorporated Background: In vivo models of deep vein thrombosis (DVT) have been described in rodents, non-human primates, and swine. However, these models typically require major surgery or they are not suitable for testing medical devices intended for humans. A large-animal model of DVT produced by minimally invasive methods may result in a more clinically-relevant model. Purpose: In this series of model development studies, we evaluated the ability to produce both primary and in-stent DVT in domestic swine between 2 and 28 days. Methods: Vascular access was obtained in the left external jugular and bilateral femoral veins. [...]