anesthesia

Curious George Goes to The Podium

2024-03-18T04:28:35-05:00

Nose Cone vs Intubated Ventilation During Open Chest Surgery in Rats – Nina Krutrök, AstraZeneca The aim of this study was to investigate if nose cone ventilation is comparable to endotracheal intubation. The latter is the most common approach for air delivery to rats undergoing open chest surgery for cardiovascular research during for example induction of myocardial infarction or epicardial injections. This method of air delivery is technically challenging leading to prolonged procedures and increased risk of endotracheal complications such as laryngeal damage and laryngeal edema, oral pharyngeal and/or tracheal laceration due to multiple intubation attempts. Nose cone ventilation is a [...]

Curious George Goes to The Podium2024-03-18T04:28:35-05:00

Fear of Neuromuscular Blocking Drugs (NMBD’s)? Let It Go, Let It Go? From Poison Arrows to Modern Day Paralytic Anesthesia

2024-03-18T04:28:36-05:00

Keynote Speaker – Dr. Scott Adrian, DVM Principal Veterinarian – Charles River Laboratories, Safety Assessment Mattawan, MI   For decades, the words “paralytics and neuromuscular blocking drugs” have stricken fear into hearts of IACUCs and animal researchers alike. As if just uttering the words would immediately summon the “demons of a regulatory inspection”.  Obviously, these fears have a basis in legitimate animal welfare concerns, and an animal should never be unjustifiably subjected to pain, distress, or discomfort without analgesic compensation and the ability to communicate that suffering should our mitigation efforts prove inadequate.  Besides the significant physiologic and anesthetic properties that [...]

Fear of Neuromuscular Blocking Drugs (NMBD’s)? Let It Go, Let It Go? From Poison Arrows to Modern Day Paralytic Anesthesia2024-03-18T04:28:36-05:00
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