non-traditional species

The Sheep as a Model for Assessing Long Term Functional Patency and Maintenance of Arteriovenous Grafts

2024-03-18T04:28:35-05:00

Speaker - John Carney University of Minnesota   Patients with end stage renal disease often require vascular grafts to create arteriovenous (AV) shunts for hemodialysis access. However, graft complications frequently occur resulting in loss of functional patency and need for subsequent interventions. Although sheep have been used to evaluate preclinical graft safety, research lacks regarding use for prolonged graft maintenance and postoperative interventions. We sought to validate the sheep model in evaluating chronic AV graft patency and salvage techniques using clinically established approaches. Methods: Methods: Three (n = 3) adult sheep weighing 88 ± 21kg and 14 ± 1 months old [...]

The Sheep as a Model for Assessing Long Term Functional Patency and Maintenance of Arteriovenous Grafts2024-03-18T04:28:35-05:00

Automated Blood Sampling in a Telemetry Cardiovascular Dog Colony

2024-03-18T04:28:36-05:00

Speaker - Amanda Wilsey Abbvie   Implementation of Automated Blood Sampling (ABS) allows for uninterrupted cardiovascular data collection with simultaneous blood collection throughout a telemetry dog preclinical study. This reduction shortens study timelines, minimizes CV data artifacts, and considerably reduces compound synthesis and the associated costs. Methods: A colony of telemetry instrumented male beagle dogs were implanted and maintained in-house for non-GLP preclinical cardiovascular safety studies. Evaluation of the ABS telemetry dog cardiovascular model; highlighting the benefits and downfalls of the last seven years since implementing Automated Blood Sampling. Results:  Since 2016, telemetry dogs implanted with transmitters and vascular access ports [...]

Automated Blood Sampling in a Telemetry Cardiovascular Dog Colony2024-03-18T04:28:36-05:00

Surgery in Zoo and Wildlife Settings: From the Outback to Balboa Park

2022-09-27T10:16:21-05:00

Surgeries in Zoo and Wildlife settings present unique challenges, from a wide array of anatomic and physical challenges to the n=1 conundrum. Dr. Reed from the San Diego Zoo will share cases she has encountered during her career in Australian wildlife hospitals, aquaria, and now in a large American zoo. With an emphasis on avian orthopedic fracture repair, approaches to surgery and post operative care in non-traditional species (including invertebrates, fish, large carnivores, and megavertebrates) will be discussed.

Surgery in Zoo and Wildlife Settings: From the Outback to Balboa Park2022-09-27T10:16:21-05:00
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