Technical Insights for Cochlear Administration in the NHP

Auditory related health conditions have warranted the development of new treatments and drugs including, for example, gene therapy focusing on restoring the sensory receptors of the auditory and vestibular systems known as hair cells. However, accessing and treating the cochlea containing these hair cells offers a formidable surgical challenge. This presentation will introduce anatomical features, landmarks, and dosing techniques for the cochlea. Surgical hints are shared but also pitfalls that may be encountered when developing and performing these dosing procedures are also discussed.